INHIBITION OF MAD2L1 MEDIATES PULMONARY FIBROSIS THROUGH IMPAIRMENT OF MITOCHONDRIAL FUNCTION AND INDUCTION OF CELL SENESCENCE

Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence

Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading to alveolar destruction in the lungs.Mitotic arrest deficient 2 like 1 (MAD2L1) is a component

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The Small Acceptance Vertex Detector of NA61/SHINE

Charmonium production in heavy ion collisions is considered as an important diagnostic probe for studying the phase diagram of strongly interacting matter for potential phase transitions.The interpretation of existing data from the CERN SPS is hampered by a lack of knowledge on the properties of open charm particle production in the fireball.Moreov

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Antioxidant potential and identification of active compounds on Kabau seed (Archidendron bubalinum) flesh and husk extract

Kabau (Archidendron bubalinum) is one of the plants that is often used as food ingredients and has the potential to be developed in the health sector.This study aims to determine the antioxidant potential of kabau seeds using 2,2-diphenyl-1-picril hidrazil (DPPH) and ferric reducing bushranger awning ability power (FRAP) methods and to identify act

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Panfacial trauma: management of a traumatic hemifacial avulsion and degloving injury with multiple maxillofacial fractures

Background: Cases of avulsion and degloving injuries of solitary areas of the face have been reported in the literature.However, complex traumatic degloving hemifacial injury with compound panfacial fractures is very rare.Rehabilitation of extensive degloving facial injuries poses a great challenge for surgeons.Surgery becomes more challenging if t

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